The study surveyed the influence of Facebook in mass mobilization of Nigerian youth in participating in ENDSARS protest. It was an established fact that social especially Facebook, was largely explored for mass mobilization and campaigns for ENDSARS protect in Nigeria. The study was anchored on Technology Determinism and Social Media Viral Model. The survey research method was used alongside 379 questionnaire that were administered to students of University of Uyo using Krejcie & Morgan formula to determine the sample size after which quota sampling was adopted. The data collected were analyzed using Frequency and Percentage Method. The main finding of the study was that social media especially Facebook was largely used for mobilization for ENDSARS protect while majority of the respondents agreed that they were first mobilized online before physical campaign. The study recommended that social media should not be restricting by law to let people voice their opinions on matters.